Dysregulated Microglial Cell Activation and Proliferation Following Repeated Antigen Stimulation

Upon reactivation of quiescent neurotropic viruses antigen (Ag)-specific brain resident-memory CD8+ T-cells (bT(RM)) may respond to de novo-produced viral Ag through the rapid release of IFN-γ, which drives subsequent interferon-stimulated gene expression in surrounding microglia. Through this mecha...

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Detalles Bibliográficos
Autores principales: Prasad, Sujata, Sheng, Wen S., Hu, Shuxian, Chauhan, Priyanka, Lokensgard, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383069/
https://www.ncbi.nlm.nih.gov/pubmed/34447297
http://dx.doi.org/10.3389/fncel.2021.686340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383069/
https://www.ncbi.nlm.nih.gov/pubmed/34447297
http://dx.doi.org/10.3389/fncel.2021.686340

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