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Loss of Foxc1 and Foxc2 function in chondroprogenitor cells disrupts endochondral ossification

Endochondral ossification initiates the growth of the majority of the mammalian skeleton and is tightly controlled through gene regulatory networks. The forkhead box transcription factors Foxc1 and Foxc2 regulate aspects of osteoblast function in the formation of the skeleton, but their roles in cho...

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Detalles Bibliográficos
Autores principales: Almubarak, Asra, Lavy, Rotem, Srnic, Nikola, Hu, Yawen, Maripuri, Devi Priyanka, Kume, Tsutomo, Berry, Fred B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383119/
https://www.ncbi.nlm.nih.gov/pubmed/34331943
http://dx.doi.org/10.1016/j.jbc.2021.101020