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Sex-Specific Association of the X Chromosome With Cognitive Change and Tau Pathology in Aging and Alzheimer Disease

IMPORTANCE: The X chromosome represents 5% of the human genome in women and men, and its influence on cognitive aging and Alzheimer disease (AD) is largely unknown. OBJECTIVE: To determine whether the X chromosome is associated with sex-specific cognitive change and tau pathology in aging and AD. DE...

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Detalles Bibliográficos
Autores principales: Davis, Emily J., Solsberg, Caroline W., White, Charles C., Miñones-Moyano, Elena, Sirota, Marina, Chibnik, Lori, Bennett, David A., De Jager, Philip L., Yokoyama, Jennifer S., Dubal, Dena B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383157/
https://www.ncbi.nlm.nih.gov/pubmed/34424272
http://dx.doi.org/10.1001/jamaneurol.2021.2806