Rufomycin Exhibits Dual Effects Against Mycobacterium abscessus Infection by Inducing Host Defense and Antimicrobial Activities

Nontuberculous mycobacterial pulmonary infection is often aggravated due to antibiotic resistance issues. There is a need for development of new drugs inducing both host immune responses and antimicrobial activities. This study shows that the rufomycins 4/5/6/7 (Rufomycin 4–7), which targets ClpC1 a...

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Detalles Bibliográficos
Autores principales: Park, Cho Rong, Paik, Seungwha, Kim, Young Jae, Kim, Jin Kyung, Jeon, Sang Min, Lee, Sang-Hee, Whang, Jake, Cheng, Jinhua, Suh, Joo-Won, Cao, Jin, Shetye, Gauri, Chen, Shao-Nong, McAlpine, James, Pauli, Guido F., Franzblau, Scott, Cho, Sanghyun, Jo, Eun-Kyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383285/
https://www.ncbi.nlm.nih.gov/pubmed/34447358
http://dx.doi.org/10.3389/fmicb.2021.695024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383285/
https://www.ncbi.nlm.nih.gov/pubmed/34447358
http://dx.doi.org/10.3389/fmicb.2021.695024

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