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PUM1 Is Overexpressed in Colon Cancer Cells With Acquired Resistance to Cetuximab
BACKGROUND: Cetuximab is an effective antibody to treat colorectal cancer (CRC) by targeting the epidermal growth factor receptor (EGFR). However, the mechanisms of acquired resistance to cetuximab therapy, especially in patients without identifiable gene mutations, are not fully understood. METHODS...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383298/ https://www.ncbi.nlm.nih.gov/pubmed/34447749 http://dx.doi.org/10.3389/fcell.2021.696558 |