Epigenetic Deregulation of the Histone Methyltransferase KMT5B Contributes to Malignant Transformation in Glioblastoma

Glioblastoma multiforme (GBM) is the most common and aggressive type of brain tumor in adulthood. Epigenetic mechanisms are known to play a key role in GBM although the involvement of histone methyltransferase KMT5B and its mark H4K20me2 has remained largely unexplored. The present study shows that...

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Detalles Bibliográficos
Autores principales: López, Virginia, Tejedor, Juan Ramón, Carella, Antonella, García, María G., Santamarina-Ojeda, Pablo, Pérez, Raúl F., Mangas, Cristina, Urdinguio, Rocío G., Aranburu, Aitziber, de la Nava, Daniel, Corte-Torres, María D., Astudillo, Aurora, Mollejo, Manuela, Meléndez, Bárbara, Fernández, Agustín F., Fraga, Mario F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383299/
https://www.ncbi.nlm.nih.gov/pubmed/34447744
http://dx.doi.org/10.3389/fcell.2021.671838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383299/
https://www.ncbi.nlm.nih.gov/pubmed/34447744
http://dx.doi.org/10.3389/fcell.2021.671838

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