In Vivo Induction of P-Glycoprotein Function can be Measured with [(18)F]MC225 and PET

[Image: see text] P-Glycoprotein (P-gp) is an efflux pump located at the blood–brain barrier (BBB) that contributes to the protection of the central nervous system by transporting neurotoxic compounds out of the brain. A decline in P-gp function has been related to the pathogenesis of neurodegenerat...

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Detalles Bibliográficos
Autores principales: García-Varela, Lara, Rodríguez-Pérez, Manuel, Custodia, Antía, Moraga-Amaro, Rodrigo, Colabufo, Nicola A., Aguiar, Pablo, Sobrino, Tomás, Dierckx, Rudi A.J.O., van Waarde, Aren, Elsinga, Philip H., Luurtsema, Gert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383301/
https://www.ncbi.nlm.nih.gov/pubmed/34228458
http://dx.doi.org/10.1021/acs.molpharmaceut.1c00302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383301/
https://www.ncbi.nlm.nih.gov/pubmed/34228458
http://dx.doi.org/10.1021/acs.molpharmaceut.1c00302

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