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Photoinduced Skeletal Rearrangement of N-Substituted Colchicine Derivatives

[Image: see text] Colchicine is an active pharmaceutical ingredient widely used for treating gout, pericarditis, and familial Mediterranean fever with high antimitotic activity. The photoisomerization of colchicine deactivates its anti-inflammatory and antimitotic properties. However, despite numero...

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Detalles Bibliográficos
Autores principales: Czerwonka, Dominika, Sobczak, Szymon, Pędziński, Tomasz, Maj, Ewa, Wietrzyk, Joanna, Celewicz, Lech, Katrusiak, Andrzej, Huczyński, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383305/
https://www.ncbi.nlm.nih.gov/pubmed/33350834
http://dx.doi.org/10.1021/acs.joc.0c02507