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Photoinduced Skeletal Rearrangement of N-Substituted Colchicine Derivatives
[Image: see text] Colchicine is an active pharmaceutical ingredient widely used for treating gout, pericarditis, and familial Mediterranean fever with high antimitotic activity. The photoisomerization of colchicine deactivates its anti-inflammatory and antimitotic properties. However, despite numero...
Autores principales: | Czerwonka, Dominika, Sobczak, Szymon, Pędziński, Tomasz, Maj, Ewa, Wietrzyk, Joanna, Celewicz, Lech, Katrusiak, Andrzej, Huczyński, Adam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2020
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383305/ https://www.ncbi.nlm.nih.gov/pubmed/33350834 http://dx.doi.org/10.1021/acs.joc.0c02507 |
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