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MicroRNA-221 regulates cell activity and apoptosis in acute lymphoblastic leukemia via regulating PTEN

T cell acute lymphoblastic leukemia (T-ALL), an aggressive and heterogeneous malignancy originating from T cell precursors (thymocytes), accounts for ~15% of all ALL cases in children and for ~25% in adults. The present study aimed to investigate the role of microRNA-221 (miR-221) in the regulation...

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Detalles Bibliográficos
Autores principales: Zhang, Lingyan, Bu, Zibin, Shen, Juan, Shang, Liping, Chen, Yuanyuan, Zhang, Ping, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383336/
https://www.ncbi.nlm.nih.gov/pubmed/34504582
http://dx.doi.org/10.3892/etm.2021.10567