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Repetitive Mild Traumatic Brain Injury in Rats Impairs Cognition, Enhances Prefrontal Cortex Neuronal Activity, and Reduces Pre-synaptic Mitochondrial Function

A major hurdle preventing effective interventions for patients with mild traumatic brain injury (mTBI) is the lack of known mechanisms for the long-term cognitive impairment that follows mTBI. The closed head impact model of repeated engineered rotational acceleration (rCHIMERA), a non-surgical anim...

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Detalles Bibliográficos
Autores principales: Feng, Yin, Li, Keguo, Roth, Elizabeth, Chao, Dongman, Mecca, Christina M., Hogan, Quinn H., Pawela, Christopher, Kwok, Wai-Meng, Camara, Amadou K. S., Pan, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383341/
https://www.ncbi.nlm.nih.gov/pubmed/34447298
http://dx.doi.org/10.3389/fncel.2021.689334