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TPMT and NUDT15 polymorphisms in thiopurine induced leucopenia in inflammatory bowel disease: a prospective study from India

BACKGROUND: Polymorphisms in thiopurine methyltransferase (TPMT) and Nudix hydrolase-15 (NUDT15) have been implicated as the predominant cause of thiopurine induced leukopenia in the Western countries and East Asia respectively. Exact role of these polymorphisms in South Asian population with inflam...

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Detalles Bibliográficos
Autores principales: Grover, Narinder, Bhatia, Prateek, Kumar, Antriksh, Singh, Minu, Lad, Deepesh, Mandavdhare, Harshal S., Samanta, Jayanta, Prasad, Kaushal K., Dutta, Usha, Sharma, Vishal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383411/
https://www.ncbi.nlm.nih.gov/pubmed/34425754
http://dx.doi.org/10.1186/s12876-021-01900-8