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Transformation From Adenocarcinoma to Pleomorphic Carcinoma as an Acquired Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors

Pulmonary pleomorphic carcinoma is a very rare histological type of primary lung cancer, and usually provides aggressive clinical courses. A 65-year-old Japanese woman was diagnosed by transbronchial biopsy of the primary tumor as c-stage IV (cT4N3M1b) of adenocarcinoma harboring L858R point mutatio...

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Detalles Bibliográficos
Autores principales: Nishimatsu, Kanako, Minami, Seigo, Ihara, Shoichi, Yasuoka, Hironao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383589/
https://www.ncbi.nlm.nih.gov/pubmed/34434479
http://dx.doi.org/10.14740/jmc3710