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EGFR DNA Methylation Correlates With EGFR Expression, Immune Cell Infiltration, and Overall Survival in Lung Adenocarcinoma

BACKGROUND: The epidermal growth factor receptor (EGFR) is a primary target of molecular targeted therapy for lung adenocarcinoma (LUAD). The mechanisms that lead to epigenetic abnormalities of EGFR in LUAD are still unclear. The purpose of our study was to evaluate the abnormal methylation of EGFR...

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Detalles Bibliográficos
Autores principales: Xu, Zhanyu, Qin, Fanglu, Yuan, Liqiang, Wei, Jiangbo, Sun, Yu, Qin, Junqi, Deng, Kun, Zheng, Tiaozhan, Li, Shikang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383738/
https://www.ncbi.nlm.nih.gov/pubmed/34447695
http://dx.doi.org/10.3389/fonc.2021.691915