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Insight Into the Molecular Mechanism of Podophyllotoxin Derivatives as Anticancer Drugs

Podophyllotoxin (PTOX) is a biologically active compound derived from the podophyllum plant, and both it and its derivatives possess excellent antitumor activity. The PTOX derivatives etoposide (VP-16) and teniposide (VM-26) have been approved by the U.S. Food and Drug Administration (FDA) for cance...

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Detalles Bibliográficos
Autores principales: Fan, Hua-yang, Zhu, Zhuo-li, Xian, Hong-chun, Wang, Hao-fan, Chen, Bing-jun, Tang, Ya-Jie, Tang, Ya-ling, Liang, Xin-hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383743/
https://www.ncbi.nlm.nih.gov/pubmed/34447752
http://dx.doi.org/10.3389/fcell.2021.709075