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Insight Into the Molecular Mechanism of Podophyllotoxin Derivatives as Anticancer Drugs
Podophyllotoxin (PTOX) is a biologically active compound derived from the podophyllum plant, and both it and its derivatives possess excellent antitumor activity. The PTOX derivatives etoposide (VP-16) and teniposide (VM-26) have been approved by the U.S. Food and Drug Administration (FDA) for cance...
Autores principales: | Fan, Hua-yang, Zhu, Zhuo-li, Xian, Hong-chun, Wang, Hao-fan, Chen, Bing-jun, Tang, Ya-Jie, Tang, Ya-ling, Liang, Xin-hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383743/ https://www.ncbi.nlm.nih.gov/pubmed/34447752 http://dx.doi.org/10.3389/fcell.2021.709075 |
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