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Neonatal Maternal Separation Modifies Proteostasis Marker Expression in the Adult Hippocampus

Exposure to early-life stress (ELS) can persistently modify neuronal circuits and functions, and contribute to the expression of misfolded and aggregated proteins that are hallmarks of several neurodegenerative diseases. The healthy brain is able to clear dysfunctional proteins through the ubiquitin...

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Detalles Bibliográficos
Autores principales: Sierra-Fonseca, Jorge A., Hamdan, Jameel N., Cohen, Alexis A., Cardenas, Sonia M., Saucedo, Sigifredo, Lodoza, Gabriel A., Gosselink, Kristin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383781/
https://www.ncbi.nlm.nih.gov/pubmed/34447296
http://dx.doi.org/10.3389/fnmol.2021.661993