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Neonatal Maternal Separation Modifies Proteostasis Marker Expression in the Adult Hippocampus
Exposure to early-life stress (ELS) can persistently modify neuronal circuits and functions, and contribute to the expression of misfolded and aggregated proteins that are hallmarks of several neurodegenerative diseases. The healthy brain is able to clear dysfunctional proteins through the ubiquitin...
Autores principales: | Sierra-Fonseca, Jorge A., Hamdan, Jameel N., Cohen, Alexis A., Cardenas, Sonia M., Saucedo, Sigifredo, Lodoza, Gabriel A., Gosselink, Kristin L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383781/ https://www.ncbi.nlm.nih.gov/pubmed/34447296 http://dx.doi.org/10.3389/fnmol.2021.661993 |
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