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Single-cell imaging of T cell immunotherapy responses in vivo

T cell immunotherapies have revolutionized treatment for a subset of cancers. Yet, a major hurdle has been the lack of facile and predicative preclinical animal models that permit dynamic visualization of T cell immune responses at single-cell resolution in vivo. Here, optically clear immunocompromi...

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Detalles Bibliográficos
Autores principales: Yan, Chuan, Yang, Qiqi, Zhang, Songfa, Millar, David G., Alpert, Eric J., Do, Daniel, Veloso, Alexandra, Brunson, Dalton C., Drapkin, Benjamin J., Stanzione, Marcello, Scarfò, Irene, Moore, John C., Iyer, Sowmya, Qin, Qian, Wei, Yun, McCarthy, Karin M., Rawls, John F., Dyson, Nick J., Cobbold, Mark, Maus, Marcela V., Langenau, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383813/
https://www.ncbi.nlm.nih.gov/pubmed/34415995
http://dx.doi.org/10.1084/jem.20210314