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Altered Ocular Fibrillin Microfibril Composition in Mice With a Glaucoma-Causing Mutation of Adamts10

PURPOSE: Previously, we identified a G661R mutation of ADAMTS10 (a disintegrin-like and metalloprotease with thrombospondin type 1 motif 10) as being disease causative in a colony of Beagles with inherited primary open-angle glaucoma (POAG). Mutations in ADAMTS10 are known to cause Weill–Marchesani...

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Detalles Bibliográficos
Autores principales: Wu, Hang-Jing, Mortlock, Douglas P., Kuchtey, Rachel W., Kuchtey, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383930/
https://www.ncbi.nlm.nih.gov/pubmed/34424262
http://dx.doi.org/10.1167/iovs.62.10.26