Synthesis of 1,2-Aminoalcohols through Enantioselective Aminoallylation of Ketones by Cu-Catalyzed Reductive Coupling

[Image: see text] Herein, we report the development of a catalytic enantioselective addition of N-substituted allyl equivalents to ketone electrophiles through use of Cu-catalyzed reductive coupling to access important chiral 1,2-aminoalcohol synthons in high levels of regio-, diastereo-, and enanti...

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Detalles Bibliográficos
Autores principales: Klake, Raphael K., Edwards, Mytia D., Sieber, Joshua D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384047/
https://www.ncbi.nlm.nih.gov/pubmed/34347500
http://dx.doi.org/10.1021/acs.orglett.1c02258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384047/
https://www.ncbi.nlm.nih.gov/pubmed/34347500
http://dx.doi.org/10.1021/acs.orglett.1c02258

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