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Simulating PIP(2)-Induced Gating Transitions in Kir6.2 Channels
ATP-sensitive potassium (K(ATP)) channels consist of an inwardly rectifying K(+) channel (Kir6.2) pore, to which four ATP-sensitive sulfonylurea receptor (SUR) domains are attached, thereby coupling K(+) permeation directly to the metabolic state of the cell. Dysfunction is linked to neonatal diabet...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384051/ https://www.ncbi.nlm.nih.gov/pubmed/34447786 http://dx.doi.org/10.3389/fmolb.2021.711975 |