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Simulating PIP(2)-Induced Gating Transitions in Kir6.2 Channels

ATP-sensitive potassium (K(ATP)) channels consist of an inwardly rectifying K(+) channel (Kir6.2) pore, to which four ATP-sensitive sulfonylurea receptor (SUR) domains are attached, thereby coupling K(+) permeation directly to the metabolic state of the cell. Dysfunction is linked to neonatal diabet...

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Detalles Bibliográficos
Autores principales:	Bründl, Michael, Pellikan, Sarala, Stary-Weinzinger, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384051/ https://www.ncbi.nlm.nih.gov/pubmed/34447786 http://dx.doi.org/10.3389/fmolb.2021.711975

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