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Genome-wide CRISPR activation screen identifies candidate receptors for SARS-CoV-2 entry

The outbreak of coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 has created a global health crisis. SARS-CoV-2 infects varieties of tissues where the known receptor ACE2 is low or almost absent, suggesting the existence of alternative viral entry pathways. Here, we performed a genome-wide b...

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Detalles Bibliográficos
Autores principales: Zhu, Shiyou, Liu, Ying, Zhou, Zhuo, Zhang, Zhiying, Xiao, Xia, Liu, Zhiheng, Chen, Ang, Dong, Xiaojing, Tian, Feng, Chen, Shihua, Xu, Yiyuan, Wang, Chunhui, Li, Qiheng, Niu, Xuran, Pan, Qian, Du, Shuo, Xiao, Junyu, Wang, Jianwei, Wei, Wensheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science China Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384091/
https://www.ncbi.nlm.nih.gov/pubmed/34431042
http://dx.doi.org/10.1007/s11427-021-1990-5