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Bmal1 Downregulation Worsens Critical Limb Ischemia by Promoting Inflammation and Impairing Angiogenesis

Critical limb ischemia (CLI) is the most advanced clinical stage of peripheral vascular disease with high mobility and mortality. CLI patients suffer from lower extremity rest pain, ulceration, and gangrene caused by insufficient blood and oxygen supply. Seeking for effective biomarkers and therapeu...

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Detalles Bibliográficos
Autores principales: Xu, Lirong, Liu, Yutong, Cheng, Qianyun, Shen, Yang, Yuan, Ye, Jiang, Xiaolang, Li, Xu, Guo, Daqiao, Jiang, Junhao, Lin, Changpo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384109/
https://www.ncbi.nlm.nih.gov/pubmed/34447794
http://dx.doi.org/10.3389/fcvm.2021.712903