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Statins reduce castration-induced bone marrow adiposity and prostate cancer progression in bone

A fraction of patients undergoing androgen deprivation therapy (ADT) for advanced prostate cancer (PCa) will develop recurrent castrate-resistant PCa (CRPC) in bone. Strategies to prevent CRPC relapse in bone are lacking. Here we show that the cholesterol-lowering drugs statins decrease castration-i...

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Detalles Bibliográficos
Autores principales: Pan, Tianhong, Lin, Song-Chang, Lee, Yu-Chen, Yu, Guoyu, Song, Jian H., Pan, Jing, Titus, Mark, Satcher, Robert L., Panaretakis, Theocharis, Logothetis, Christopher, Yu-Lee, Li-Yuan, Lin, Sue-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384136/
https://www.ncbi.nlm.nih.gov/pubmed/34127814
http://dx.doi.org/10.1038/s41388-021-01874-7