A genetic screen in Drosophila uncovers the multifaceted properties of the NUP98-HOXA9 oncogene

Acute myeloid leukemia (AML) underlies the uncontrolled accumulation of immature myeloid blasts. Several cytogenetic abnormalities have been associated with AML. Among these is the NUP98-HOXA9 (NA9) translocation that fuses the Phe-Gly repeats of nucleoporin NUP98 to the homeodomain of the transcrip...

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Detalles Bibliográficos
Autores principales: Gavory, Gwenaëlle, Baril, Caroline, Laberge, Gino, Bidla, Gawa, Koonpaew, Surapong, Sonea, Thomas, Sauvageau, Guy, Therrien, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384169/
https://www.ncbi.nlm.nih.gov/pubmed/34383740
http://dx.doi.org/10.1371/journal.pgen.1009730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384169/
https://www.ncbi.nlm.nih.gov/pubmed/34383740
http://dx.doi.org/10.1371/journal.pgen.1009730

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