Connection of core and tail Mediator modules restrains transcription from TFIID-dependent promoters

The Mediator coactivator complex is divided into four modules: head, middle, tail, and kinase. Deletion of the architectural subunit Med16 separates core Mediator (cMed), comprising the head, middle, and scaffold (Med14), from the tail. However, the direct global effects of tail/cMed disconnection a...

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Detalles Bibliográficos
Autores principales: Saleh, Moustafa M., Jeronimo, Célia, Robert, François, Zentner, Gabriel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384189/
https://www.ncbi.nlm.nih.gov/pubmed/34383744
http://dx.doi.org/10.1371/journal.pgen.1009529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384189/
https://www.ncbi.nlm.nih.gov/pubmed/34383744
http://dx.doi.org/10.1371/journal.pgen.1009529

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