Cargando…
Connection of core and tail Mediator modules restrains transcription from TFIID-dependent promoters
The Mediator coactivator complex is divided into four modules: head, middle, tail, and kinase. Deletion of the architectural subunit Med16 separates core Mediator (cMed), comprising the head, middle, and scaffold (Med14), from the tail. However, the direct global effects of tail/cMed disconnection a...
Autores principales: | Saleh, Moustafa M., Jeronimo, Célia, Robert, François, Zentner, Gabriel E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384189/ https://www.ncbi.nlm.nih.gov/pubmed/34383744 http://dx.doi.org/10.1371/journal.pgen.1009529 |
Ejemplares similares
-
Involvement of the SAGA and TFIID coactivator complexes in transcriptional dysregulation caused by the separation of core and tail Mediator modules
por: Saleh, Moustafa M, et al.
Publicado: (2022) -
Downstream promoter interactions of TFIID TAFs facilitate transcription reinitiation
por: Joo, Yoo Jin, et al.
Publicado: (2017) -
SAGA mediates transcription from the TATA-like element independently of Taf1p/TFIID but dependent on core promoter structures in Saccharomyces cerevisiae
por: Watanabe, Kiyoshi, et al.
Publicado: (2017) -
Molecular structure of promoter-bound yeast TFIID
por: Kolesnikova, Olga, et al.
Publicado: (2018) -
Promoter-proximal nucleosomes attenuate RNA polymerase II transcription through TFIID
por: Fisher, Michael J., et al.
Publicado: (2023)