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Computational identification and experimental characterization of preferred downstream positions in human core promoters

Metazoan core promoters, which direct the initiation of transcription by RNA polymerase II (Pol II), may contain short sequence motifs termed core promoter elements/motifs (e.g. the TATA box, initiator (Inr) and downstream core promoter element (DPE)), which recruit Pol II via the general transcript...

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Detalles Bibliográficos
Autores principales: Dreos, René, Sloutskin, Anna, Malachi, Nati, Ideses, Diana, Bucher, Philipp, Juven-Gershon, Tamar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384218/
https://www.ncbi.nlm.nih.gov/pubmed/34383743
http://dx.doi.org/10.1371/journal.pcbi.1009256