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Mitochondrial fission, integrity and completion of mitophagy require separable functions of Vps13D in Drosophila neurons

A healthy population of mitochondria, maintained by proper fission, fusion, and degradation, is critical for the long-term survival and function of neurons. Here, our discovery of mitophagy intermediates in fission-impaired Drosophila neurons brings new perspective into the relationship between mito...

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Detalles Bibliográficos
Autores principales: Insolera, Ryan, Lőrincz, Péter, Wishnie, Alec J., Juhász, Gábor, Collins, Catherine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384225/
https://www.ncbi.nlm.nih.gov/pubmed/34383748
http://dx.doi.org/10.1371/journal.pgen.1009731