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Advancing therapies for viral infections using mechanistic computational models of the dynamic interplay between the virus and host immune response

The COVID-19 pandemic has highlighted a need for improved frameworks for drug discovery, repurposing, clinical trial design and therapy optimization and personalization. Mechanistic computational models can play an important role in developing these frameworks. We discuss how mechanistic models, whi...

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Detalles Bibliográficos
Autores principales: Zarnitsyna, Veronika I, Gianlupi, Juliano Ferrari, Hagar, Amit, Sego, TJ, Glazier, James A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384423/
https://www.ncbi.nlm.nih.gov/pubmed/34450519
http://dx.doi.org/10.1016/j.coviro.2021.07.007