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Advancing therapies for viral infections using mechanistic computational models of the dynamic interplay between the virus and host immune response
The COVID-19 pandemic has highlighted a need for improved frameworks for drug discovery, repurposing, clinical trial design and therapy optimization and personalization. Mechanistic computational models can play an important role in developing these frameworks. We discuss how mechanistic models, whi...
Autores principales: | Zarnitsyna, Veronika I, Gianlupi, Juliano Ferrari, Hagar, Amit, Sego, TJ, Glazier, James A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384423/ https://www.ncbi.nlm.nih.gov/pubmed/34450519 http://dx.doi.org/10.1016/j.coviro.2021.07.007 |
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