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Proinflammatory activity of TWEAK on human dermal fibroblasts and synoviocytes: blocking and enhancing effects of anti-TWEAK monoclonal antibodies

Human tumour necrosis factor (TNF)-like weak inducer of apoptosis (hTWEAK) and two anti-hTWEAK mAbs were tested for their ability to elicit or block inflammatory responses in cultured human dermal fibroblasts and synoviocytes. Incubation with hTWEAK increased the production of prostaglandin E(2), ma...

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Detalles Bibliográficos
Autores principales: Chicheportiche, Yves, Chicheportiche, Rachel, Sizing, Irene, Thompson, Jeff, Benjamin, Christopher B, Ambrose, Christine, Dayer, Jean-Michel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC83846/
https://www.ncbi.nlm.nih.gov/pubmed/11879548