Intrinsic activation of β-catenin signaling by CRISPR/Cas9-mediated exon skipping contributes to immune evasion in hepatocellular carcinoma

Comprehensive analysis of clinical samples has recently identified molecular and immunological classification of hepatocellular carcinoma (HCC), and the CTNNB1 (β-catenin)-mutated subtype exhibits distinctive characteristics of immunosuppressive tumor microenvironment. For clarifying the molecular m...

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Detalles Bibliográficos
Autores principales: Akasu, Masafumi, Shimada, Shu, Kabashima, Ayano, Akiyama, Yoshimitsu, Shimokawa, Masahiro, Akahoshi, Keiichi, Kudo, Atsushi, Yamaoka, Shoji, Tanabe, Minoru, Tanaka, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384852/
https://www.ncbi.nlm.nih.gov/pubmed/34429454
http://dx.doi.org/10.1038/s41598-021-96167-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384852/
https://www.ncbi.nlm.nih.gov/pubmed/34429454
http://dx.doi.org/10.1038/s41598-021-96167-0

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