Identification of new target proteins of a Urotensin-II receptor antagonist using transcriptome-based drug repositioning approach

Drug repositioning research using transcriptome data has recently attracted attention. In this study, we attempted to identify new target proteins of the urotensin-II receptor antagonist, KR-37524 (4-(3-bromo-4-(piperidin-4-yloxy)benzyl)-N-(3-(dimethylamino)phenyl)piperazine-1-carboxamide dihydrochl...

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Detalles Bibliográficos
Autores principales: Lim, Gyutae, Lim, Chae Jo, Lee, Jeong Hyun, Lee, Byung Ho, Ryu, Jae Yong, Oh, Kwang-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384862/
https://www.ncbi.nlm.nih.gov/pubmed/34429474
http://dx.doi.org/10.1038/s41598-021-96612-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384862/
https://www.ncbi.nlm.nih.gov/pubmed/34429474
http://dx.doi.org/10.1038/s41598-021-96612-0

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