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Humans and other commonly used model organisms are resistant to cycloheximide-mediated biases in ribosome profiling experiments
Ribosome profiling measures genome-wide translation dynamics at sub-codon resolution. Cycloheximide (CHX), a widely used translation inhibitor to arrest ribosomes in these experiments, has been shown to induce biases in yeast, questioning its use. However, whether such biases are present in datasets...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384890/ https://www.ncbi.nlm.nih.gov/pubmed/34429433 http://dx.doi.org/10.1038/s41467-021-25411-y |