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A modified density gradient proteomic-based method to analyze endolysosomal proteins in cardiac tissue
The importance of lysosomes in cardiac physiology and pathology is well established, and evidence for roles in calcium signaling is emerging. We describe a label-free proteomics method suitable for small cardiac tissue biopsies based on density-separated fractionation, which allows study of endolyso...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384914/ https://www.ncbi.nlm.nih.gov/pubmed/34466782 http://dx.doi.org/10.1016/j.isci.2021.102949 |