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Multi-layered proteogenomic analysis unravels cancer metastasis directed by MMP-2 and focal adhesion kinase signaling

The role of matrix metalloproteinase-2 (MMP-2) in tumor cell migration has been widely studied, however, the characteristics and effects of MMP-2 in clinical sample of metastatic colorectal cancer (CRC) remain poorly understood. Here, in order to unveil the perturbed proteomic signal during MMP-2 in...

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Detalles Bibliográficos
Autores principales: Kwon, Yumi, Park, Seong-Jun, Nguyen, Binh Thanh, Kim, Mi Jeong, Oh, Sejin, Lee, Hwanho, Park, Narae, Kim, Hyun Seok, Kang, Min-Jung, Min, Byung Soh, Lee, Jin-Won, Yang, Eun Gyeong, Lee, Cheolju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385024/
https://www.ncbi.nlm.nih.gov/pubmed/34429501
http://dx.doi.org/10.1038/s41598-021-96635-7