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Regional heritability mapping identifies several novel loci (STAT4, ULK4, and KCNH5) for primary biliary cholangitis in the Japanese population

While the advent of GWAS more than a decade ago has ushered in remarkable advances in our understanding of complex traits, the limitations of single-SNP analysis have also led to the development of several other approaches. Simulation studies have shown that the regional heritability mapping (RHM) m...

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Detalles Bibliográficos
Autores principales: Gervais, Olivier, Ueno, Kazuko, Kawai, Yosuke, Hitomi, Yuki, Aiba, Yoshihiro, Ueta, Mayumi, Nakamura, Minoru, Tokunaga, Katsushi, Nagasaki, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385030/
https://www.ncbi.nlm.nih.gov/pubmed/33833419
http://dx.doi.org/10.1038/s41431-021-00854-5