The structure of a dimeric form of SARS-CoV-2 polymerase

The coronavirus SARS-CoV-2 uses an RNA-dependent RNA polymerase (RdRp) to replicate and transcribe its genome. Previous structures of the RdRp revealed a monomeric enzyme composed of the catalytic subunit nsp12, two copies of subunit nsp8, and one copy of subunit nsp7. Here we report an alternative,...

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Detalles Bibliográficos
Autores principales: Jochheim, Florian A., Tegunov, Dimitry, Hillen, Hauke S., Schmitzová, Jana, Kokic, Goran, Dienemann, Christian, Cramer, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385044/
https://www.ncbi.nlm.nih.gov/pubmed/34429502
http://dx.doi.org/10.1038/s42003-021-02529-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385044/
https://www.ncbi.nlm.nih.gov/pubmed/34429502
http://dx.doi.org/10.1038/s42003-021-02529-9

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