An automated real-time microfluidic platform to probe single NK cell heterogeneity and cytotoxicity on-chip

Cytotoxicity is a vital effector mechanism used by immune cells to combat pathogens and cancer cells. While conventional cytotoxicity assays rely on averaged end-point measures, crucial insights on the dynamics and heterogeneity of effector and target cell interactions cannot be extracted, emphasizi...

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Detalles Bibliográficos
Autores principales: Subedi, Nikita, Van Eyndhoven, Laura C., Hokke, Ayla M., Houben, Lars, Van Turnhout, Mark C., Bouten, Carlijn V. C., Eyer, Klaus, Tel, Jurjen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385055/
https://www.ncbi.nlm.nih.gov/pubmed/34429486
http://dx.doi.org/10.1038/s41598-021-96609-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385055/
https://www.ncbi.nlm.nih.gov/pubmed/34429486
http://dx.doi.org/10.1038/s41598-021-96609-9

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