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An automated real-time microfluidic platform to probe single NK cell heterogeneity and cytotoxicity on-chip
Cytotoxicity is a vital effector mechanism used by immune cells to combat pathogens and cancer cells. While conventional cytotoxicity assays rely on averaged end-point measures, crucial insights on the dynamics and heterogeneity of effector and target cell interactions cannot be extracted, emphasizi...
Autores principales: | Subedi, Nikita, Van Eyndhoven, Laura C., Hokke, Ayla M., Houben, Lars, Van Turnhout, Mark C., Bouten, Carlijn V. C., Eyer, Klaus, Tel, Jurjen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385055/ https://www.ncbi.nlm.nih.gov/pubmed/34429486 http://dx.doi.org/10.1038/s41598-021-96609-9 |
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