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The landscape of alternative polyadenylation in single cells of the developing mouse embryo

3′ untranslated regions (3′ UTRs) post-transcriptionally regulate mRNA stability, localization, and translation rate. While 3′-UTR isoforms have been globally quantified in limited cell types using bulk measurements, their differential usage among cell types during mammalian development remains poor...

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Detalles Bibliográficos
Autores principales: Agarwal, Vikram, Lopez-Darwin, Sereno, Kelley, David R., Shendure, Jay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385098/
https://www.ncbi.nlm.nih.gov/pubmed/34429411
http://dx.doi.org/10.1038/s41467-021-25388-8