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The landscape of alternative polyadenylation in single cells of the developing mouse embryo
3′ untranslated regions (3′ UTRs) post-transcriptionally regulate mRNA stability, localization, and translation rate. While 3′-UTR isoforms have been globally quantified in limited cell types using bulk measurements, their differential usage among cell types during mammalian development remains poor...
Autores principales: | Agarwal, Vikram, Lopez-Darwin, Sereno, Kelley, David R., Shendure, Jay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385098/ https://www.ncbi.nlm.nih.gov/pubmed/34429411 http://dx.doi.org/10.1038/s41467-021-25388-8 |
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