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m6A demethylase FTO suppresses pancreatic cancer tumorigenesis by demethylating PJA2 and inhibiting Wnt signaling

Pancreatic cancer is the deadliest malignancy of the digestive system and is the seventh most common cause of cancer-related deaths worldwide. The incidence and mortality of pancreatic cancer continue to increase, and its 5-year survival rate remains the lowest among all cancers. N6-methyladenine (m...

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Detalles Bibliográficos
Autores principales: Zeng, Juan, Zhang, Heying, Tan, Yonggang, Wang, Zhe, Li, Yunwei, Yang, Xianghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385122/
https://www.ncbi.nlm.nih.gov/pubmed/34484859
http://dx.doi.org/10.1016/j.omtn.2021.06.005