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Quantitative trait mapping in Diversity Outbred mice identifies novel genomic regions associated with the hepatic glutathione redox system

The tripeptide glutathione (GSH) is instrumental to antioxidant protection and xenobiotic metabolism, and the ratio of its reduced and oxidized forms (GSH/GSSG) indicates the cellular redox environment and maintains key aspects of cellular signaling. Disruptions in GSH levels and GSH/GSSG have long...

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Detalles Bibliográficos
Autores principales: Gould, Rebecca L., Craig, Steven W., McClatchy, Susan, Churchill, Gary A., Pazdro, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385155/
https://www.ncbi.nlm.nih.gov/pubmed/34418604
http://dx.doi.org/10.1016/j.redox.2021.102093