Functional diagnostics using fresh uncultured lung tumor cells to guide personalized treatments

Functional profiling of a cancer patient’s tumor cells holds potential to tailor personalized cancer treatment. Here, we report the utility of fresh uncultured tumor-derived EpCAM(+) epithelial cells (FUTCs) for ex vivo drug-response interrogation. Analysis of murine Kras mutant FUTCs demonstrates p...

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Detalles Bibliográficos
Autores principales: Talwelkar, Sarang S., Mäyränpää, Mikko I., Søraas, Lars, Potdar, Swapnil, Bao, Jie, Hemmes, Annabrita, Linnavirta, Nora, Lømo, Jon, Räsänen, Jari, Knuuttila, Aija, Wennerberg, Krister, Verschuren, Emmy W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385325/
https://www.ncbi.nlm.nih.gov/pubmed/34467250
http://dx.doi.org/10.1016/j.xcrm.2021.100373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385325/
https://www.ncbi.nlm.nih.gov/pubmed/34467250
http://dx.doi.org/10.1016/j.xcrm.2021.100373

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