Investigating site-selection mechanisms of retroviral integration in supercoiled DNA braids

We theoretically study the integration of short viral DNA in a DNA braid made up by two entwined double-stranded DNA molecules. We show that the statistics of single integration events substantially differ in the straight and buckled, or plectonemic, phase of the braid and are more likely in the lat...

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Detalles Bibliográficos
Autores principales: Forte, G., Michieletto, D., Marenduzzo, D., Orlandini, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2021
Materias:
Life Sciences–Physics interface
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385341/
https://www.ncbi.nlm.nih.gov/pubmed/34428944
http://dx.doi.org/10.1098/rsif.2021.0229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385341/
https://www.ncbi.nlm.nih.gov/pubmed/34428944
http://dx.doi.org/10.1098/rsif.2021.0229

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