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Investigating site-selection mechanisms of retroviral integration in supercoiled DNA braids
We theoretically study the integration of short viral DNA in a DNA braid made up by two entwined double-stranded DNA molecules. We show that the statistics of single integration events substantially differ in the straight and buckled, or plectonemic, phase of the braid and are more likely in the lat...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385341/ https://www.ncbi.nlm.nih.gov/pubmed/34428944 http://dx.doi.org/10.1098/rsif.2021.0229 |